CIL’s Expanding Line of 99% Enriched Amino Acids for Proteomic Applications
Higher enrichments provide improved accuracy in quantitative MS-based proteomic applications. Free amino acids are used in metabolic labeling of organisms and animals for global quantitative proteomic analysis. Protected amino acids are used in the synthesis of peptides for use as internal standards for peptide identity and quantitation.
Welcome to CK Isotopes
CK Isotopes Ltd is proud to be the official distributor for Cambridge Isotope Laboratories, Inc. in the UK and Ireland. (CIL) is the world’s leading producer of stable isotopes and stable isotope-labeled compounds. With over 400 employees and laboratories in four countries, CIL specialises in the process of labeling biochemical and organic compounds with highly enriched, stable (nonradioactive) isotopes of carbon, hydrogen, nitrogen and oxygen. Our chemists substitute common atoms (e.g., 1H, 12C, 14N, 16O) with rare, highly valued isotopes (e.g., 2H, 13C, 15N, 18O) so that the final product can be readily measured or traced using mass spectrometry (mass spec) or nuclear magnetic resonance (NMR). CIL’s products are utilised in laboratories, medical, government and academic research centers and health care facilities worldwide. We are proud that CIL products have contributed to medical advancements in cancer research, new-drug development, environmental analysis, genomics and proteomics, and medical diagnostic research. In the past decade as the fields of proteomics and metabolomics have developed as leading techniques for determining biomarkers for disease presence, progression and the monitoring of therapeutic response, CIL has worked closely with industry leaders and researchers to provide the stable isotope-labeled tools needed for improved quantitation of complex systems.
CIL’s state-of-the-art production facilities are located at the company’s headquarters in Tewksbury, Massachusetts, and the company’s primary production laboratories are located in Andover, Massachusetts. Our isotope-separation facility located in Xenia, Ohio, houses the world’s largest 13C and 18O isotope-separation facilities and the world’s only commercial D2O enrichment columns.
Please use our online catalogue to search for any products of interest and browse through our area specific pages for additional information and resources. If you have any questions or would just like a chat about what you are looking to do with stable isotopes then please don’t hesitate to contact us.
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